install.packages(pkgs = "BiocManager")
BiocManager::install(pkgs = "csSAM")
install.packages(pkgs = "http://bioconductor.org/packages/3.7/bioc/src/contrib/BiocInstaller_1.30.0.tar.gz", type = "source")
install.packages(pkgs = "http://web.cbio.uct.ac.za/~renaud/CRAN/src/contrib/CellMix_1.6.2.tar.gz", type = "source")